Recombinant Human Growth Regulated Protein-beta/CXCL2

名称：Recombinant Human Growth Regulated Protein-beta/CXCL2

货号：UN197

规格：5μg/20μg/50μg/100μg/250μg/500μg/1mg

纯度：>97%

系统：E.coli.

产品详情

 Recombinant Human Growth Regulated Protein-beta/CXCL2

CXCL2, also named GRO-β, is belonging to the CXC chemokine family. CXCL2/GRO-β shares 90% amino acid sequence with CXCL1/GRO-α. All three human GROs (GRO-α, GRO-β, GRO-γ) are members of the alpha (chemokine C-X-C) subfamily of chemokine. This chemokine is secreted by monocytes and macrophages. The functional receptor for CXCL2 has been identified as CXCR2. CXCL2 is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells. Similar to other GRO proteins, CXCL2 is potent neutrophil attractants and activators. In addition, it is also active toward basophils. Recombinant human GRO-β/CXCL2 is a 7.9kDa protein containing 73 amino acid residues.

 名称缩写/Abbreviation：

rHuGRO-β/CXCL2

货号/Item No.：

UN197

表达系统/Source：

Expressed in E. coli.

分子量/Molecular Weight：

Approximately 7.9 kDa, a single non-glycosylated polypeptide chain containing 73 amino acids.

SCI的检索号/Accession #：

P19875 Ala35-Asn107

蛋白序列/A.A. Sequence：

APLATELRCQCLQTLQGIHLKNIQSVKVKSPGPHCAQTEVIATLKNGQKACLNPASPMVKKIIEKMLKNGKSN

纯度/Purity：

＞97% by SDS-PAGE or HPLC.

活性/Biological Activity：

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected human 293 cells is in a concentration range of 10-100 ng/ml.

配方/Formulation：

Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, with 150 mM NaCl, pH 7.4.

外观/Appearance：

Sterile filtered White lyophilized (freeze-dried) powder.

内毒素/Endotoxin：

< 0.1 EU/μg of rHuGRO-β/CXCL2 protein as determined by LAL method.

复溶/Reconstitution：

Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.

稳定性和存储/Stability & Storage：

For long term storage, the product should be stored ≤ -20℃. Please avoid repeated freeze-thaw cycles after reconstitution. 36 months from date of receipt, -20 to -70℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -70℃ under sterile conditions after reconstitution.

* THIS PRODUCT IS FOR RESEARCH, LABORATORY AND EVALUATION PURPOSE ONLY.