ecombinant Human Growth Regulated Protein-alpha/CXCL1

名称：Recombinant Human Growth Regulated Protein-alpha/CXCL1

货号：UN196

规格：5μg/20μg/50μg/100μg/250μg/500μg/1mg

纯度：>97%

系统：E.coli.

产品详情

 Recombinant Human Growth Regulated Protein-alpha/CXCL1

CXCL1 is belonging to the CXC chemokine family. It is encoded by the GRO gene now designated CXCL1. All three human GROs (GRO-α, GRO-β, GRO-γ) are members of the alpha (chemokine C-X-C) subfamily of chemokine. This chemokine is secreted by monocytes and macrophages. CXCL1 is secreted by human melanoma cells, and also expressed by macrophages, neutrophils and epithelial cells. CXCL1 has chemotactic activity for neutrophils, and plays a role in inflammation and wound healing. The functional receptor for CXCL1 has been identified as CXCR2. Recombinant human GRO-α/CXCL1 is a 7.9kDa protein containing 73 amino acid residues.

 名称缩写/Abbreviation：

rHuGRO-α/CXCL1

货号/Item No.：

UN196

别名/Synonyms：

GROα, MGSA, NAP-3

表达系统/Source：

Expressed in E. coli.

分子量/Molecular Weight：

Approximately 7.9 kDa, a single non-glycosylated polypeptide chain containing 73 amino acids.

SCI的检索号/Accession #：

P09341 Ala35-Asn107

蛋白序列/A.A. Sequence：

ASVATELRCQCLQTLQGIHPKNIQSVNVKSPGPHCAQTEVIATLKNGRKACLNPASPIVKKIIEKMLNSDKSN

纯度/Purity：

＞97% by SDS-PAGE or HPLC.

活性/Biological Activity：

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood neutrophils is in a concentration range of 10-50 ng/ml

配方/Formulation：

Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, with 150 mM NaCl, pH 7.4.

外观/Appearance：

Sterile filtered White lyophilized (freeze-dried) powder.

内毒素/Endotoxin：

< 0.01 EU/μg of rHuGRO-α/CXCL1 protein as determined by LAL method.

复溶/Reconstitution：

Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.

稳定性和存储/Stability & Storage：

For long term storage, the product should be stored ≤ -20℃. Please avoid repeated freeze-thaw cycles after reconstitution. 36 months from date of receipt, -20 to -70℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -70℃ under sterile conditions after reconstitution.

* THIS PRODUCT IS FOR RESEARCH, LABORATORY AND EVALUATION PURPOSE ONLY.