Recombinant Human Fractalkine/CX3CL1

名称：Recombinant Human Fractalkine/CX3CL1

货号：UN213

规格：5μg/20μg/50μg/100μg/250μg/500μg/1mg

纯度：>98%

系统：E.coli.

产品详情

 Recombinant Human Fractalkine/CX3CL1

CX3CL1 recently identified through bioinformatics is the only known member of the CX3C chemokine family and it is also commonly known under the names fractalkine (in humans) and neurotactin (in mice). Unlike other known chemokines, CX3CL1 is a type 1 membrane protein containing a chemokine domain tethered on a long mucinlike talk. The soluble form of CX3CL1 is chemotactic for T-cells and monocytes, but not for neutrophils. In addition, it may play a role in regulating leukocyte adhesion and migration processes at the endothelium. Human CX3CL1 shares approximately 78% and 83% amino acid sequence homology with the murine and rat protein. Recombinant Human CX3CL1?is an 8.6kDa protein containing 76 amino acid residues.

 名称缩写/Abbreviation：

rHuFractalkine/CX3CL1

货号/Item No.：

UN213

别名/Synonyms：

C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Neurotactin, Small-inducible cytokine D1

表达系统/Source：

Expressed in E. coli.

分子量/Molecular Weight：

Approximately 8.6 kDa, a single non-glycosylated polypeptide chain containing 76 amino acids.

SCI的检索号/Accession #：

P78423 Gln25-Gly10⁰

蛋白序列/A.A. Sequence：

QHHGVTKCNITCSKMTSKIPVALLIHYQQNQASCGKRAIILETRQHRLFCADPKEQWVKDAMQHLDRQAA ALTRNG

纯度/Purity：

＞98% by SDS-PAGE or HPLC.

活性/Biological Activity：

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 5.0-10 ng/ml.

配方/Formulation：

Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH7.4.

外观/Appearance：

Sterile filtered White lyophilized (freeze-dried) powder.

内毒素/Endotoxin：

< 0.1 EU/μg of rHuFractalkine/CX3CL1 protein as determined by LAL method.

复溶/Reconstitution：

Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.

稳定性和存储/Stability & Storage：

For long term storage, the product should be stored ≤ -20℃. Please avoid repeated freeze-thaw cycles after reconstitution. 36 months from date of receipt, -20 to -70℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -70℃ under sterile conditions after reconstitution.

* THIS PRODUCT IS FOR RESEARCH, LABORATORY AND EVALUATION PURPOSE ONLY.