Recombinant Human Cuteaneous T-cell Attracting Chemokine/CCL27

名称：Recombinant Human Cuteaneous T-cell Attracting Chemokine/CCL27

货号：UN190

规格：5μg/20μg/50μg/100μg/500μg/1mg

纯度：>96%

系统：E.coli.

产品详情

Recombinant Human Cuteaneous T-cell Attracting Chemokine/CCL27

CCL27, also named IL-11 R-alpha-locus chemokine (ILC) , Skinkine, ESkine and cutaneous T-cell-attracting chemokine (CTACK) , is a small cytokine belonging to the CC chemokine family. CCL27 is expressed in numerous tissues, including gonads, thymus, placenta and skin and it elicits its chemotactic effects by binding to the chemokine receptor CCR10. CCL27 can attract skin-associated memory T-lymphocytes. Studies showed it may play a role in mediating homing of lymphocytes to cutaneous sites and cell migration during embryogenesis. Mature human CCL27 is an 88 amino acid (a.a.) protein that shares 56% a.a. sequence identity with murine. Recombinant Human CTACK is a 10.2kDa protein containing 88 amino acid residues.

名称缩写/Abbreviation：

rHuCTACK/CCL27

货号/Item No.：

UN190

别名/Synonyms：

Cutaneous T-cell Attracting Chemokine, CCL27, ALP, Skinkine, ESkine

表达系统/Source：

Expressed in E. coli.

分子量/Molecular Weight：

Approximately 10.1 kDa, a single non-glycosylated polypeptide chain containing 88 amino acids.

SCI的检索号/Accession #：

Q9Y4X3 Phe25-Gly112

蛋白序列/A.A. Sequence：

FLLPPSTACCTQLYRKPLSDKLLRKVIQVELQEADGDCHLQAFVLHLAQRSICIHPQNPSLSQWFEHQERKLHGTLPKLNFGMLRKMG

纯度/Purity：

＞96% by SDS-PAGE or HPLC.

活性/Biological Activity：

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using CCR10 transfected BaF3 cells is in a concentration range of 10-100 ng/ml.

配方/Formulation：

Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.0.

外观/Appearance：

Sterile filtered White lyophilized (freeze-dried) powder.

内毒素/Endotoxin：

< 0.01 EU/μg of rHuCTACK/CCL27 protein as determined by LAL method.

复溶/Reconstitution：

Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.

稳定性和存储/Stability & Storage：

For long term storage, the product should be stored ≤ -20℃. Please avoid repeated freeze-thaw cycles after reconstitution. 36 months from date of receipt, -20 to -70℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -70℃ under sterile conditions after reconstitution.

* THIS PRODUCT IS FOR RESEARCH, LABORATORY AND EVALUATION PURPOSE ONLY.