Recombinant Human BCA-1/CXCL13

名称：Recombinant Human BCA-1/CXCL13

货号：UN209

规格：5μg/20μg/50μg/100μg/250μg/500μg/1mg

纯度：>97%

系统：E.coli

产品详情

Recombinant Human BCA-1/CXCL13

C-X-C motif chemokine 13 encoded by the CXCL13 gene located on human chromosome 4 is constitutively expressed in secondary lymphoid organs. It is also known as B lymphocyte chemoattractant (BLC) . As its name suggests, CXCL13 is selectively chemotactic for B cells belonging to both the B-1 and B-2 subsets, and elicits its effects by interacting with chemokine receptor CXCR5. It and its receptor CXCR5 control the organization of B cells within follicles of lymphoid tissues. Mature human BCA-1 shares 64 % amino acid sequence similarity with the murine protein and 23–34 % amino acid sequence identity with other known CXC chemokines. Recombinant human BCA-1/CXCL13 is a 10.3kDa protein containing 87 amino acid residues.

名称缩写/Abbreviation：  

rHuBCA-1/CXCL13

货号/Item No.：  

UN209

表达系统/Source：  

Expressed in E. coli.

分子量/Molecular Weight：  

Approximately 10.3 kDa, a single non-glycosylated polypeptide chain containing 87 amino acids.

SCI的检索号/Accession #：  

O43927 Val23-Pro109

蛋白序列/A.A. Sequence：  

VLEVYYTSLRCRCVQESSVFIPRRFIDRIQILPRGNGCPRKEIIVWKKNKSIVCVDPQAEWIQRMMEVLRKRSSSTLPVPVFKRKIP

纯度/Purity：  

＞97% by SDS-PAGE or HPLC.

活性/Biological Activity：  

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human B cells is in a concentration range of 1.0-10 ng/ml.

配方/Formulation：  

Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.

外观/Appearance：  

Sterile filtered White lyophilized (freeze-dried) powder.

内毒素/Endotoxin：  

< 0.1 EU/μg of rHuBCA-1/CXCL13 protein as determined by LAL method.

复溶/Reconstitution：  

Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.

稳定性和存储/Stability & Storage：  

For long term storage, the product should be stored ≤ -20℃. Please avoid repeated freeze-thaw cycles after reconstitution. 36 months from date of receipt, -20 to -70℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -70℃ under sterile conditions after reconstitution.

* THIS PRODUCT IS FOR RESEARCH, LABORATORY AND EVALUATION PURPOSE ONLY.