Recombinant Murine Beta-defensin 14

名称：Recombinant Murine Beta-defensin 14

货号：UN449

规格：5μg/20μg/50μg/100μg/250μg/500μg/1mg

纯度：>97%

系统：E.coli.

产品详情

Recombinant Murine Beta-defensin 14

Mouse Beta-defensin 14 (BD-14) is a small, positively charged peptide that plays a crucial role in the innate immune system. It is primarily expressed in various epithelial tissues and immune cells, where it provides broad-spectrum antimicrobial protection against bacteria, fungi, and certain viruses. Beyond its direct antimicrobial activity, BD-14 also serves as an immune modulator, acting as a chemotactic factor to attract immune cells and influencing immune signaling pathways. This multifunctional peptide is essential for maintaining mucosal health, regulating inflammatory responses, and contributes to the body's first line of defense against pathogen invasion.

名称缩写/Abbreviation：  

rMuBD-14

货号/Item No.：  

UN449

表达系统/Source：  

Expressed in E. coli.

分子量/Molecular Weight：  

Approximately 5.2 kDa, a single non-glycosylated polypeptide chain containing 45 amino acids.

SCI的检索号/Accession #：  

Q7TNV9

蛋白序列/A.A. Sequence：  

FLPKTLRKFF CRIRGGRCAV LNCLGKEEQI GRCSNSGRKC CRKKK

纯度/Purity：  

＞97% by SDS-PAGE or HPLC.

配方/Formulation：  

Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.

外观/Appearance：  

Sterile filtered White lyophilized (freeze-dried) powder.

内毒素/Endotoxin：  

< 0.01 EU/μg of rMuBD-14 protein as determined by LAL method.

复溶/Reconstitution：  

Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.

稳定性和存储/Stability & Storage：  

For long term storage, the product should be stored ≤ -20℃. Please avoid repeated freeze-thaw cycles after reconstitution. 36 months from date of receipt, -20 to -70℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -70℃ under sterile conditions after reconstitution.

* THIS PRODUCT IS FOR RESEARCH, LABORATORY AND EVALUATION PURPOSE ONLY.