Recomb inant Human Platelet Factor-4/CXCL4

名称：Recomb inant Human Platelet Factor-4/CXCL4

货号：UN199

规格：5μg/20μg/50μg/100μg/250μg/500μg/1mg

产品详情

Recombinant Human Platelet Factor-4/CXCL4

Platelet Factor-4 (PF-4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4) . The gene for human CXCL4 is located on human chromosome 4. This chemokine is released from alpha-granules of activated platelets during platelet aggregation and neutralizes the anticoagulant effect of heparin. It interacts with a splice variant of the chemokine receptor CXCR3 besides be chemotactic for neutrophils, fibroblasts and monocytes. Specifically, Human and mouse CXCL4 share about a 60% identity. Recombinant humanPF-4/CXCL4 is a 7.8kDa protein containing 70 amino acid residues.

名称缩写/Abbreviation：

rHuPF-4/CXCL4

货号/Item No.：

UN199

别名/Synonyms：

Iroplact, Oncostatin-A

表达系统/Source：

Expressed in E. coli.

分子量/Molecular Weight：

Approximately 7.8 kDa, a single non-glycosylated polypeptide chain containing 70 amino acids.

SCI的检索号/Accession #：

P02776 Ala32-Asn101

蛋白序列/A.A. Sequence：

EAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES

纯度/Purity：

＞97% by SDS-PAGE or HPLC.

活性/Biological Activity：

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human fibroblasts is in a concentration of 1.0-10 ng/ml.

配方/Formulation：

Lyophilized from a 0.2 μm filtered concentrated solution in Acetonitrile and TFA.

外观/Appearance：

Sterile filtered White lyophilized (freeze-dried) powder.

内毒素/Endotoxin：

< 0.1 EU/μg of rHuPF-4/CXCL4 protein as determined by LAL method.

复溶/Reconstitution：

Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.

稳定性和存储/Stability & Storage：

For long term storage, the product should be stored ≤ -20℃. Please avoid repeated freeze-thaw cycles after reconstitution. 36 months from date of receipt, -20 to -70℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -70℃ under sterile conditions after reconstitution.

* THIS PRODUCT IS FOR RESEARCH, LABORATORY AND EVALUATION PURPOSE ONLY.