Recombinant Human Prolactin

名称：Recombinant Human Prolactin

货号：UN149

规格：10μg/50μg/100μg/250μg/500μg/1mg

纯度：>98%

系统：E.coli.

产品详情

Recombinant Human Prolactin

Prolactin (gene name PRL) is a secreted neuroendocrine pituitary hormone that acts primarily on the mammary gland to promote lactation, but has pleiotropic effects in both males and females. Its primary function is to promote and maintain lactation during pregnancy and suckling. In addition, prolactin plays an immunoregulatory role by stimulating the activities of ornithine decarboxylase and protein kinase C, which are important for the proliferation, differentiation, and function of lymphocytes. Human prolactin shares only 60% and 63% amino acid sequence identity with mouse and rat prolactin, respectively, although rat prolactin can activate the human prolactin receptor. Recombinant Human Prolactin is a 23.0kDa globular protein containing 200 amino acid residues.

 名称缩写/Abbreviation：

rHuProlactin

货号/Item No.：

UN149

别名/Synonyms：

Mammotropin, Luteotropic hormone, Luteotropin

表达系统/Source：

Expressed in E. coli.

分子量/Molecular Weight：

Approximately 23.0 kDa, a single non-glycosylated polypeptide chain containing 200 amino acids.

SCI的检索号/Accession #：

P01236 Leu29-Cys227 with an N-terminal Met

蛋白序列/A.A. Sequence：

MLPICPGGAARCQVTLRDLFDRAVVLSHYIHNLSSEMFSEFDKRYTHGRGFITKAINSCHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWNEPLYHLVTEVRGMQEAPEAILSKAVEIEEQTKRLLEGMELIVSQVHPETKENEIYPVWSGLPSLQMADEESRLSAYYNLLHCLRRDSHKIDNYLKLLKCRIIHNNNC

纯度/Purity：

＞98% by SDS-PAGE or HPLC.

活性/Biological Activity：

Fully biologically active when compared to standard. Determined by its ability to induce the proliferation of rat Nb2-11 cells in the concentration range of 0.1-1.0 ng/ml..

配方/Formulation：

Lyophilized from a 0.2 μm filtered concentrated solution in PBS.

外观/Appearance：

Sterile filtered White lyophilized (freeze-dried) powder.

内毒素/Endotoxin：

< 0.01 EU/μg of rHuProlactin protein as determined by LAL method.

复溶/Reconstitution：

Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.

稳定性和存储/Stability & Storage：

For long term storage, the product should be stored ≤ -20℃. Please avoid repeated freeze-thaw cycles after reconstitution. 36 months from date of receipt, -20 to -70℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -70℃ under sterile conditions after reconstitution.

* THIS PRODUCT IS FOR RESEARCH, LABORATORY AND EVALUATION PURPOSE ONLY.