Recombinant Human Activation-induced TNFR Member Ligand/TNFSF18

名称：Recombinant Human Activation-induced TNFR Member Ligand/TNFSF18

货号：UN411

规格：5μg/20μg/50μg/100μg/500μg/1mg

纯度：>98%

系统：E.coli.

产品详情

 Recombinant Human Activation-induced TNFR Member Ligand/TNFSF18

Human Activation-induced TNFR member Ligand/TNFSF18, also named as AITRL, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family and it is encoded by the TNFSF18 gene. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. It is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. human AITRL/TNFSF18 shares 56% and 60% AA sequence identity with murine and rat TNFSF18, respectively. Recombinant human TNFSF18 is a 14.3kDa protein, containing 126 amino acid residues.

名称缩写/Abbreviation：

rHuAITR Ligand/TNFSF18

货号/Item No.：

UN411

别名/Synonyms：

Activation-Induced TNFR member Ligand, TNFSF18, GITRL, TL-6

表达系统/Source：

Expressed in E. coli.

分子量/Molecular Weight：

Approximately 14.3 kDa, a single non-glycosylated polypeptide chain containing 126 amino acids.

SCI的检索号/Accession #：

Q9UNG2 Glu74-Ser199

蛋白序列/A.A. Sequence：

ETAKEPCMAKFGPLPSKWQMASSEPPCVNKVSDWKLEILQNGLYLIYGQVAPNANYNDVAPFEVRLYKNKDMIQTLTNKSKIQNVGGTYELHVGDTIDLIFNSEHQVLKNNTYWGIILLANPQFIS

纯度/Purity：

＞98% by SDS-PAGE or HPLC.

活性/Biological Activity：

Fully biologically active when compared to standard. The biological activity as determined by stimulation of IL-8 production using human PBMC is in a concentration range of 0.1-10 ng/ml.

配方/Formulation：

Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, with 150 mM NaCl, pH 7.4.

外观/Appearance：

Sterile filtered White lyophilized (freeze-dried) powder.

内毒素/Endotoxin：

< 0.01 EU/μg of rHuAITR Ligand/TNFSF18 protein as determined by LAL method.

复溶/Reconstitution：

Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.

稳定性和存储/Stability & Storage：

For long term storage, the product should be stored ≤ -20℃. Please avoid repeated freeze-thaw cycles after reconstitution. 36 months from date of receipt, -20 to -70℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -70℃ under sterile conditions after reconstitution.

* THIS PRODUCT IS FOR RESEARCH, LABORATORY AND EVALUATION PURPOSE ONLY.