Recombinant Porcine Interferon-alpha1b

名称：Recombinant Porcine Interferon-alpha1b

货号：UN100

规格：5μg/20μg/50μg/100μg/1mg

纯度：>96%

系统：E.coli.

产品详情

Recombinant Porcine Interferon-alpha1b

IFN-αs are proteins secreted by leukocyte. They are mainly involved in innate immune response against viral infection. The IFN-α family has 13 subtypes and 23 different variants. The individual proteins have molecular masses between 19-26kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-alpha subtypes differ in their sequences at only one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. The recombinant porcine IFN-α1 is a 19.15kDa protein consisting of 166 amino acid residues.

 名称缩写/Abbreviation：

rPoIFN-α1b

货号/Item No.：

UN100

别名/Synonyms：

Interferon alpha‐2, Interferon alpha A, Type I interferon

表达系统/Source：

Expressed in E. coli.

分子量/Molecular Weight：

Approximately 19.15 kDa, a single non-glycosylated polypeptide chain containing 166 amino acids.

SCI的检索号/Accession #：

P49879 Cys24-Glu189

蛋白序列/A.A. Sequence：

CDLPQTHSLAHTRALRLLAQMRRISPFSCLDHRRDFGSPHEAFGGNQVQKAQAMALVHEMLQQTFQLFSTEGSAAAWNESLLHQFYTGLDQQLRDLEACVMQEAGLEGTPLLEEDSIRAVRKYFHRLTLYLQEKSYSPCAWEIVRAEVMRSFSSSRNLQDRLRKKE

纯度/Purity：

＞96% by SDS-PAGE or HPLC.

配方/Formulation：

Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM Tris-HCL, 300 mM NaCl, 0.02% (v/v) Tween-20, pH 8.5.

外观/Appearance：

Sterile filtered White lyophilized (freeze-dried) powder.

内毒素/Endotoxin：

< 0.1 EU/μg of rPoIFN-α1b protein as determined by LAL method.

复溶/Reconstitution：

Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.

稳定性和存储/Stability & Storage：

For long term storage, the product should be stored ≤ -20℃. Please avoid repeated freeze-thaw cycles after reconstitution. 36 months from date of receipt, -20 to -70℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -70℃ under sterile conditions after reconstitution.

* THIS PRODUCT IS FOR RESEARCH, LABORATORY AND EVALUATION PURPOSE ONLY.