Recombinant Human Glia Maturation Factor beta

名称：Recombinant Human Glia Maturation Factor beta

货号：UN298

规格：2μg/10μg/50μg/100μg/500μg/1mg

纯度：>96%

系统：E.coli.

产品详情

 Recombinant Human Glia Maturation Factor beta

The glia maturation factor beta belongs to the actin-binding proteins ADF family, GMF subfamily. It contains an ADF-H domain, but the research of crystallography and NMR reveals that there are structures different between human and mouse ADF-H domain. GMF-β appears to play a role in the differentiation, maintenance, and regeneration of the nervous system. It also supports the progression of certain auto immune diseases, possibly through its ability to induce the production and secretion of various pro inflammatory cytokines. It also inhibition of proliferation of tumor cells and it has also been shown to function intracellularly as a modulator of MAP kinase signal transduction. Recombinant human GMFβis a 16.6kDa protein containing 141 amino-acid residues.

 名称缩写/Abbreviation：

rHuGMF-β

货号/Item No.：

UN298

别名/Synonyms：

Glia Maturation Factor beta, GMFB

表达系统/Source：

Expressed in E. coli.

分子量/Molecular Weight：

Approximately 16.6 kDa, a single non-glycosylated polypeptide chain containing 141 amino acids.

SCI的检索号/Accession #：

P60983 Ser2-His142

蛋白序列/A.A. Sequence：

SESLVVCDVAEDLVEKLRKFRFRKETNNAAIIMKIDKDKRLVVLDEELEGISPDELKDELPERQPRFIVYSYKYQHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNKLVQTAELTKVFEIRNTEDLTEEWLREKLGFFH

纯度/Purity：

＞96% by SDS-PAGE or HPLC.

配方/Formulation：

Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, with 150 mM NaCl, pH 7.4.

外观/Appearance：

Sterile filtered White lyophilized (freeze-dried) powder.

内毒素/Endotoxin：

< 0.1 EU/μg of rHuGMF-βprotein as determined by LAL method.

复溶/Reconstitution：

Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.

稳定性和存储/Stability & Storage：

For long term storage, the product should be stored ≤ -20℃. Please avoid repeated freeze-thaw cycles after reconstitution. 36 months from date of receipt, -20 to -70℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -70℃ under sterile conditions after reconstitution.

* THIS PRODUCT IS FOR RESEARCH, LABORATORY AND EVALUATION PURPOSE ONLY.